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8YX9

CD40 in complex with Dacetuzumab Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(H, B, E, G)
Dacetuzumab, Heavy chainpolymer22323858.74Homo sapiens
2B, D, F, H
(L, C, F, I)
Dacetuzumab, light chainpolymer21924025.74Homo sapiens
3I, J, K, L
(A, D, J, K)
Tumor necrosis factor receptor superfamily member 5polymer17920016.34UniProt (P25942)
Pfam (PF00020)
Homo sapiens (human)B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40
4M, N, O, P, Q...
(H, B, E, A, D...)
GLYCEROLnon-polymer92.17Chemie (GOL)
5AA, BA, CA, DA, EA...
(I, A, D, J, K...)
waterwater18.058Chemie (HOH)
Sequence modifications
A, D, J, K: 21 - 193 (UniProt: P25942)
PDBExternal DatabaseDetails
His 194-expression tag
His 195-expression tag
His 196-expression tag
His 197-expression tag
His 198-expression tag
His 199-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight271602.9
Non-Polymers*Number of molecules7
Total formula weight644.7
All*Total formula weight272247.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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