8YX9
CD40 in complex with Dacetuzumab Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (H, B, E, G) | Dacetuzumab, Heavy chain | polymer | 223 | 23858.7 | 4 | Homo sapiens | ||
| 2 | B, D, F, H (L, C, F, I) | Dacetuzumab, light chain | polymer | 219 | 24025.7 | 4 | Homo sapiens | ||
| 3 | I, J, K, L (A, D, J, K) | Tumor necrosis factor receptor superfamily member 5 | polymer | 179 | 20016.3 | 4 | UniProt (P25942) Pfam (PF00020) | Homo sapiens (human) | B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40 |
| 4 | M, N, O, P, Q... (H, B, E, A, D...) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | AA, BA, CA, DA, EA... (I, A, D, J, K...) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A, D, J, K: 21 - 193 (UniProt: P25942)
| PDB | External Database | Details |
|---|---|---|
| His 194 | - | expression tag |
| His 195 | - | expression tag |
| His 196 | - | expression tag |
| His 197 | - | expression tag |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 271602.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 644.7 | |
| All* | Total formula weight | 272247.5 |
