8YX9

CD40 in complex with Dacetuzumab Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H, B, E, G	Dacetuzumab, Heavy chain	polymer	223	23858.7	4		Homo sapiens
2	L, C, F, I	Dacetuzumab, light chain	polymer	219	24025.7	4		Homo sapiens
3	A, D, J, K	Tumor necrosis factor receptor superfamily member 5	polymer	179	20016.3	4	UniProt (P25942) Pfam (PF00020) In PDB	Homo sapiens (human)	B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40
4	H, B, E, A, D...	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
5		water	water		18.0	58	Chemie (HOH)

Sequence modifications

A, D, J, K: 21 - 193 (UniProt: P25942)

PDB	External Database	Details
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	271602.9
Non-Polymers*	Number of molecules	7
	Total formula weight	644.7
All*	Total formula weight	272247.5

*Water molecules are not included.