8YX9
CD40 in complex with Dacetuzumab Fab
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042113 | biological_process | B cell activation |
| A | 0050776 | biological_process | regulation of immune response |
| D | 0009897 | cellular_component | external side of plasma membrane |
| D | 0038023 | molecular_function | signaling receptor activity |
| D | 0042113 | biological_process | B cell activation |
| D | 0050776 | biological_process | regulation of immune response |
| J | 0009897 | cellular_component | external side of plasma membrane |
| J | 0038023 | molecular_function | signaling receptor activity |
| J | 0042113 | biological_process | B cell activation |
| J | 0050776 | biological_process | regulation of immune response |
| K | 0009897 | cellular_component | external side of plasma membrane |
| K | 0038023 | molecular_function | signaling receptor activity |
| K | 0042113 | biological_process | B cell activation |
| K | 0050776 | biological_process | regulation of immune response |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR197-HIS203 | |
| H | TYR195-HIS201 |
| site_id | PS00652 |
| Number of Residues | 34 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Crekq..Ylinsq.....C..Csl.Cqpgqklvsd..Cteft..ETEC |
| Chain | Residue | Details |
| A | CYS26-CYS59 |
| site_id | PS01186 |
| Number of Residues | 14 |
| Details | EGF_2 EGF-like domain signature 2. CtCeeGWhctsea..C |
| Chain | Residue | Details |
| A | CYS103-CYS116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 140 |
| Details | Repeat: {"description":"TNFR-Cys 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 126 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 80 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
