8YWQ
Crystal structure of the Fab fragment of the anti-IL-6 antibody I9H in complex with a domain-swapped IL-6 dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Heavy chain of the Fab fragment of anti-IL-6 antibody I9H | polymer | 231 | 24912.1 | 1 | Homo sapiens | ||
| 2 | B (L) | Light chain of the Fab fragment of anti-IL-6 antibody I9H | polymer | 214 | 23397.0 | 1 | Homo sapiens | ||
| 3 | C (A) | Interleukin-6 | polymer | 185 | 21006.0 | 1 | UniProt (P05231) Pfam (PF00489) | Homo sapiens (human) | IL-6,B-cell stimulatory factor 2,BSF-2,CTL differentiation factor,CDF,Hybridoma growth factor,Interferon beta-2,IFN-beta-2 |
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 69315.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 69339.3 |
