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8YU7

Cryo-EM structure of CXCR4 tetramer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
C-X-C chemokine receptor type 4polymer35139656.24UniProt (P61073)
Pfam (PF12109)
Pfam (PF00001)
Homo sapiens (human)CXC-R4,CXCR-4,FB22,Fusin,HM89,LCR1,Leukocyte-derived seven transmembrane domain receptor,LESTR,Lipopolysaccharide-associated protein 3,LAP-3,LPS-associated protein 3,NPYRL,Stromal cell-derived factor 1 receptor,SDF-1 receptor
2E, F, G, H, I...
(A, B, C, D)
CHOLESTEROLnon-polymer386.720Chemie (CLR)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight158624.8
Non-Polymers*Number of molecules20
Total formula weight7733.1
All*Total formula weight166357.9
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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