8YTD
Crystal Structure of TrkA D5 domain in complex with two different macrocyclic peptides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity nerve growth factor receptor | polymer | 102 | 11221.6 | 1 | UniProt (P04629) | Homo sapiens (human) | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
| 2 | B (B) | Macrocyclic Peptide | polymer | 15 | 1677.0 | 1 | synthetic construct | ||
| 3 | C (C) | Macrocyclic Peptide | polymer | 18 | 2231.5 | 1 | synthetic construct | ||
| 4 | D, E, F, G (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | H, I, J (A, B, C) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 15130.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.3 | |
| All* | Total formula weight | 15378.3 |
