8YT8
Cryo-EM structure of the dystrophin glycoprotein complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-sarcoglycan | polymer | 291 | 32539.2 | 1 | UniProt (P82350) Pfam (PF05510) Pfam (PF20989) | Mus musculus (house mouse) | Alpha-SG,50 kDa dystrophin-associated glycoprotein,50DAG,Adhalin |
| 2 | B (B) | Beta-sarcoglycan | polymer | 263 | 28730.0 | 1 | UniProt (P82349) Pfam (PF04790) | Mus musculus (house mouse) | Beta-SG,43 kDa dystrophin-associated glycoprotein,43DAG |
| 3 | C (C) | Dystrobrevin alpha | polymer | 206 | 23363.2 | 1 | UniProt (Q9D2N4) Pfam (PF09068) Pfam (PF09069) | Mus musculus (house mouse) | DTN-A,Alpha-dystrobrevin |
| 4 | D (D) | Delta-sarcoglycan | polymer | 263 | 29191.1 | 1 | UniProt (P82347) Pfam (PF04790) | Mus musculus (house mouse) | Delta-SG,35 kDa dystrophin-associated glycoprotein,35DAG |
| 5 | E (E) | Dystrophin | polymer | 331 | 38371.4 | 1 | UniProt (P11531) Pfam (PF00569) Pfam (PF00397) Pfam (PF09068) Pfam (PF09069) | Mus musculus (house mouse) | |
| 6 | F (G) | Gamma-sarcoglycan | polymer | 265 | 28956.2 | 1 | UniProt (P82348) Pfam (PF04790) | Mus musculus (house mouse) | Gamma-SG,35 kDa dystrophin-associated glycoprotein,35DAG |
| 7 | G (I) | unknown segment | polymer | 5 | 559.7 | 1 | Mus musculus (house mouse) | ||
| 8 | H (O) | Beta-dystroglycan | polymer | 289 | 31934.5 | 1 | UniProt (Q62165) Pfam (PF05454) | Mus musculus (house mouse) | Beta-DG |
| 9 | I (S) | Sarcospan | polymer | 179 | 19918.0 | 1 | UniProt (Q62147) Pfam (PF04103) | Mus musculus (house mouse) | K-ras oncogene-associated protein,Kirsten-Ras-associated protein |
| 10 | J, M, N, O, P (F, K, L, M, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 11 | K (H) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB | |||
| 12 | L, R (J, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 13 | Q (P) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G44266EX) | |||
| 14 | S, T, Y (A, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 15 | AA, U, V (S, D) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (45044259) PubChem (49853509) PubChem (50990013) PubChem (176980071) PubChem (18640088) PubChem (52934537) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (44654663) PubChem (46937002) PubChem (56621683) PubChem (59274407) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (1551269) PubChem (90070115) PubChem (59450329) PubChem (59628412) PubChem (117965027) PubChem (6432564) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (132837164) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (304) PubChem (138967089) PubChem (139566851) PubChem (89951918) PubChem (90224410) PubChem (15939944) PubChem (91298236) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (638019) PubChem (101624109) PubChem (1549081) PubChem (1553803) PubChem (171828367) PubChem (173516975) PubChem (124225449) PubChem (124429284) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (6419195) PubChem (6994560) PubChem (130459183) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (131992107) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (139568882) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 16 | W (E) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 17 | X (G) | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 1 | Chemie (P5S) PubChem (9547096) PubChem (15409341) PubChem (165429904) PubChem (125040277) PubChem (9547075) PubChem (133612130) PubChem (10417847) | |||
| 18 | Z (O) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 233563.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4954.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2721.1 | |
| All* | Total formula weight | 241238.9 |
