8YT8
Cryo-EM structure of the dystrophin glycoprotein complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-sarcoglycan | polymer | 291 | 32539.2 | 1 | UniProt (P82350) Pfam (PF05510) Pfam (PF20989) | Mus musculus (house mouse) | Alpha-SG,50 kDa dystrophin-associated glycoprotein,50DAG,Adhalin |
| 2 | B (B) | Beta-sarcoglycan | polymer | 263 | 28730.0 | 1 | UniProt (P82349) Pfam (PF04790) | Mus musculus (house mouse) | Beta-SG,43 kDa dystrophin-associated glycoprotein,43DAG |
| 3 | C (C) | Dystrobrevin alpha | polymer | 206 | 23363.2 | 1 | UniProt (Q9D2N4) Pfam (PF09068) Pfam (PF09069) | Mus musculus (house mouse) | DTN-A,Alpha-dystrobrevin |
| 4 | D (D) | Delta-sarcoglycan | polymer | 263 | 29191.1 | 1 | UniProt (P82347) Pfam (PF04790) | Mus musculus (house mouse) | Delta-SG,35 kDa dystrophin-associated glycoprotein,35DAG |
| 5 | E (E) | Dystrophin | polymer | 331 | 38371.4 | 1 | UniProt (P11531) Pfam (PF00569) Pfam (PF00397) Pfam (PF09068) Pfam (PF09069) | Mus musculus (house mouse) | |
| 6 | F (G) | Gamma-sarcoglycan | polymer | 265 | 28956.2 | 1 | UniProt (P82348) Pfam (PF04790) | Mus musculus (house mouse) | Gamma-SG,35 kDa dystrophin-associated glycoprotein,35DAG |
| 7 | G (I) | unknown segment | polymer | 5 | 559.7 | 1 | Mus musculus (house mouse) | ||
| 8 | H (O) | Beta-dystroglycan | polymer | 289 | 31934.5 | 1 | UniProt (Q62165) Pfam (PF05454) | Mus musculus (house mouse) | Beta-DG |
| 9 | I (S) | Sarcospan | polymer | 179 | 19918.0 | 1 | UniProt (Q62147) Pfam (PF04103) | Mus musculus (house mouse) | K-ras oncogene-associated protein,Kirsten-Ras-associated protein |
| 10 | J, M, N, O, P (F, K, L, M, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 11 | K (H) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB | |||
| 12 | L, R (J, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 13 | Q (P) | beta-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G44266EX) | |||
| 14 | S, T, Y (A, O) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 15 | AA, U, V (S, D) | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
| 16 | W (E) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 17 | X (G) | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 1 | Chemie (P5S) | |||
| 18 | Z (O) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 233563.2 | |
| Branched | Number of molecules | 9 |
| Total formula weight | 4954.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2721.1 | |
| All* | Total formula weight | 241238.9 |
