8YRP

SARS-CoV-2 Delta Spike in complex with JM-1A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Spike glycoprotein	polymer	1259	139421.5	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	n	JM-1A Heavy Chain	polymer	115	12411.9	1		Homo sapiens
3	o	JM-1A Light Chain	polymer	105	11275.5	1		Homo sapiens

Sequence modifications

A, B, C: 14 - 1206 (UniProt: P0DTC2)

PDB	External Database	Details
Met -5	-	expression tag
Lys -4	-	expression tag
Val -3	-	expression tag
Lys -2	-	expression tag
Leu -1	-	expression tag
Leu 0	-	expression tag
Val 1	-	expression tag
Leu 2	-	expression tag
Leu 3	-	expression tag
Cys 4	-	expression tag
Thr 5	-	expression tag
Phe 6	-	expression tag
Thr 7	-	expression tag
Ala 8	-	expression tag
Thr 9	-	expression tag
Tyr 10	-	expression tag
Ala 11	-	expression tag
Gly 12	-	expression tag
Thr 13	-	expression tag
Arg 19	Thr 19	variant
Asp 142	Gly 142	variant
-	Glu 156	deletion
-	Phe 157	deletion
Gly 156	Arg 158	variant
Arg 450	Leu 452	variant
Lys 476	Thr 478	variant
Gly 612	Asp 614	variant
Arg 679	Pro 681	variant
Gly 680	Arg 682	variant
Ser 681	Arg 683	variant
Gly 683	Arg 685	variant
Asn 948	Asp 950	variant
Pro 984	Lys 986	variant
Pro 985	Val 987	variant
Asp 1207	-	expression tag
Ile 1208	-	expression tag
Arg 1209	-	expression tag
Ser 1210	-	expression tag
Leu 1211	-	expression tag
Val 1212	-	expression tag
Pro 1213	-	expression tag
Arg 1214	-	expression tag
Gly 1215	-	expression tag
Ser 1216	-	expression tag
Pro 1217	-	expression tag
Gly 1218	-	expression tag
Ser 1219	-	expression tag
Gly 1220	-	expression tag
Tyr 1221	-	expression tag
Ile 1222	-	expression tag
Pro 1223	-	expression tag
Glu 1224	-	expression tag
Ala 1225	-	expression tag
Pro 1226	-	expression tag
Arg 1227	-	expression tag
Asp 1228	-	expression tag
Gly 1229	-	expression tag
Gln 1230	-	expression tag
Ala 1231	-	expression tag
Tyr 1232	-	expression tag
Val 1233	-	expression tag
Arg 1234	-	expression tag
Lys 1235	-	expression tag
Asp 1236	-	expression tag
Gly 1237	-	expression tag
Glu 1238	-	expression tag
Trp 1239	-	expression tag
Val 1240	-	expression tag
Leu 1241	-	expression tag
Leu 1242	-	expression tag
Ser 1243	-	expression tag
Thr 1244	-	expression tag
Phe 1245	-	expression tag
Leu 1246	-	expression tag
Gly 1247	-	expression tag
His 1248	-	expression tag
His 1249	-	expression tag
His 1250	-	expression tag
His 1251	-	expression tag
His 1252	-	expression tag
His 1253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	441952.0
All*	Total formula weight	441952.0

*Water molecules are not included.