8YQD
Crystal structure of human transthyretin variant A97S in complex with Tafamidis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 124 | 13438.0 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | C, D (A, B) | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid | non-polymer | 308.1 | 2 | Chemie (3MI) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 124 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ser 97 | Ala 117 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26875.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 616.2 | |
| All* | Total formula weight | 27492.1 |
