8YP5
The structure of MAP2K4 complexed with 5Z7-oxozeaenol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity mitogen-activated protein kinase kinase 4 | polymer | 327 | 37471.0 | 1 | UniProt (P45985) Pfam (PF00069) | Homo sapiens (human) | MAP kinase kinase 4,MAPKK 4,JNK-activating kinase 1,MAPK/ERK kinase 4,MEK 4,SAPK/ERK kinase 1,SEK1,Stress-activated protein kinase kinase 1,SAPK kinase 1,SAPKK-1,SAPKK1,c-Jun N-terminal kinase kinase 1,JNKK |
| 2 | B (A) | (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione | non-polymer | 362.4 | 1 | Chemie (1FM) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 80 - 399 (UniProt: P45985)
| PDB | External Database | Details |
|---|---|---|
| Met 79 | - | initiating methionine |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37471.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 37857.7 |
