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8YLE

Crystal structure of Werner syndrome helicase complexed with AMP-PCP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRNpolymer43049003.51UniProt (Q14191)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF16124)
Homo sapiens (human)DNA helicase,RecQ-like type 3,RecQ protein-like 2,Werner syndrome protein
2B
(A)
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERnon-polymer505.21Chemie (ACP)
3C, D
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
4E, F
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
5G
(A)
waterwater18.0235Chemie (HOH)
Sequence modifications
A: 0 - 428 (UniProt: Q14191)
PDBExternal DatabaseDetails
Ala 429-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49003.5
Non-Polymers*Number of molecules5
Total formula weight760.2
All*Total formula weight49763.6
*Water molecules are not included.

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PDB entries from 2024-11-13

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