8YGQ
Crystal structure of Human TEAD2 in complex with Cobimetinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcriptional enhancer factor TEF-4 | polymer | 226 | 25729.2 | 2 | UniProt (Q15562) Pfam (PF17725) | Homo sapiens (human) | TEA domain family member 2,TEAD-2 |
| 2 | C (A) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 3 | D (B) | [3,4-BIS(FLUORANYL)-2-[(2-FLUORANYL-4-IODANYL-PHENYL)AMINO]PHENYL]-[3-OXIDANYL-3-[(2S)-PIPERIDIN-2-YL]AZETIDIN-1-YL]METHANONE | non-polymer | 531.3 | 1 | Chemie (EUI) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51458.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 787.7 | |
| All* | Total formula weight | 52246.1 |
