8YDD
Crystal structure of Nanog(R100A) in complex with Wdr5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | WD repeat-containing protein 5 | polymer | 313 | 34391.0 | 3 | UniProt (P61965) Pfam (PF00400) | Mus musculus (house mouse) | BMP2-induced 3-kb gene protein,WD repeat-containing protein BIG-3 |
| 2 | D, E (D, E) | Homeobox protein NANOG | polymer | 61 | 7443.8 | 2 | UniProt (Q80Z64) Pfam (PF00046) | Mus musculus (house mouse) | ES cell-associated protein 4,Early embryo specific expression NK-type homeobox protein,Homeobox transcription factor Nanog |
| 3 | F, G, H, I, J (A, B, C, D, E) | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
D, E: 96 - 155 (UniProt: Q80Z64)
| PDB | External Database | Details |
|---|---|---|
| Ser 95 | - | expression tag |
| Ala 100 | Arg 100 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 118060.5 | |
| All* | Total formula weight | 118060.5 |
