8Y8V

Cryo-EM structure of AQP7 in POPC nanodisc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Green fluorescent protein,Aquaporin-7	polymer	607	67259.1	1	UniProt (P42212) UniProt (O14520) Pfam (PF00230)	Aequorea victoria	AQP-7,Aquaglyceroporin-7,Aquaporin adipose,AQPap,Aquaporin-7-like
2	B (A)	O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine	non-polymer		792.1	1	Chemie (P5S)

Sequence modifications

A: -252 - -14 (UniProt: P42212)

PDB	External Database	Details
Met -264	-	initiating methionine
Gly -263	-	expression tag
Ser -262	-	expression tag
Ser -261	-	expression tag
His -260	-	expression tag
His -259	-	expression tag
His -258	-	expression tag
His -257	-	expression tag
His -256	-	expression tag
His -255	-	expression tag
His -254	-	expression tag
His -253	-	expression tag
Val -251	-	insertion
Leu -188	Phe 64	engineered mutation
Thr -187	Ser 65	engineered mutation
Lys -46	Ala 206	engineered mutation
Leu -21	His 231	engineered mutation
Ser -13	-	linker
Ser -12	-	linker
Gly -11	-	linker
Glu -10	-	linker
Asn -9	-	linker
Leu -8	-	linker
Tyr -7	-	linker
Phe -6	-	linker
Gln -5	-	linker
Gly -4	-	linker
His -3	-	linker
Met -2	-	linker
Ala -1	-	linker
Ser 0	-	linker

A: 1 - 342 (UniProt: O14520)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	67259.1
Non-Polymers*	Number of molecules	1
	Total formula weight	792.1
All*	Total formula weight	68051.2

*Water molecules are not included.