8Y6F

The crystal structure of MMPs cleavable human heavy chain ferritin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Ferritin	polymer	196	22709.2	12	UniProt (Q6NZ44) Pfam (PF00210) UniProt (by SIFTS) (P02794)	Homo sapiens (human)
2	IA, M, N, W (L, A, E)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
3	AA, BA, CA, DA, FA... (H, I, J, K, L...)	FE (III) ION	non-polymer		55.8	17	Chemie (FE)
4	EA, JA, R, T (J, L, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
5	LA, MA, NA, OA, PA... (A, B, C, D, E...)	water	water		18.0	2521	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 189 (UniProt: Q6NZ44)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Gly 163	-	insertion
Pro 164	-	insertion
Leu 165	-	insertion
Gly 166	-	insertion
Leu 167	-	insertion
Ala 168	-	insertion
Gly 169	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	272510.7
Non-Polymers*	Number of molecules	25
	Total formula weight	1183.1
All*	Total formula weight	273693.9

*Water molecules are not included.