8Y31

The crystal structure of the QX006N-Fab/IFNAR1-SD123 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	QX006N-Fab-LC	polymer	216	23200.7	2		Homo sapiens (human)
2	B, D (B, D)	QX006N-Fab-HC	polymer	230	24517.5	2		Homo sapiens (human)
3	E, F (E, F)	Interferon alpha/beta receptor 1	polymer	346	39767.2	2	UniProt (P17181) Pfam (PF01108) Pfam (PF09294)	Homo sapiens (human)	IFN-R-1,IFN-alpha/beta receptor 1,Cytokine receptor class-II member 1,Cytokine receptor family 2 member 1,CRF2-1,Type I interferon receptor 1
4	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	68	Chemie (HOH)

Sequence modifications

E, F: 1 - 333 (UniProt: P17181)

PDB	External Database	Details
Glu 334	-	expression tag
Val 335	-	expression tag
Leu 336	-	expression tag
Phe 337	-	expression tag
Gln 338	-	expression tag
Gly 339	-	expression tag
Pro 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag
His 345	-	expression tag
His 346	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	174970.9
All*	Total formula weight	174970.9

*Water molecules are not included.