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8Y0V

HIF prolyl hydroxylase 2 in complex with inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Egl nine homolog 1polymer24627525.31UniProt (Q9GZT9)
Pfam (PF13640)
Homo sapiens (human)Hypoxia-inducible factor prolyl hydroxylase 2,HIF-PH2,HIF-prolyl hydroxylase 2,HPH-2,Prolyl hydroxylase domain-containing protein 2,PHD2,SM-20
2B
(A)
~{tert}-butyl 4-[6-[(6-cyanopyridin-3-yl)methylcarbamoyl]-5-oxidanyl-1,7-naphthyridin-2-yl]piperazine-1-carboxylatenon-polymer489.51Chemie (A1D5X)
3C
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
4D
(A)
waterwater18.039Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight27525.3
Non-Polymers*Number of molecules2
Total formula weight544.5
All*Total formula weight28069.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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