8XV6
Crystal structure of PHD domain of UHRF1 in complex with mStella peptide (residues 85-119)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | E3 ubiquitin-protein ligase UHRF1 | polymer | 75 | 8332.4 | 2 | UniProt (Q96T88) Pfam (PF00628) | Homo sapiens (human) | Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,HuNp95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 2 | B, D (B, D) | Developmental pluripotency-associated protein 3 | polymer | 35 | 4299.2 | 2 | UniProt (Q8QZY3) | Mus musculus | Compaction-associated protein 1,Primordial germ cell protein 7,Stella |
| 3 | E, F, G, N, O... (A, C, D) | THIOCYANATE ION | non-polymer | 58.1 | 6 | Chemie (SCN) | |||
| 4 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I, J, K, L, M... (A, C) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 6 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A, C: 298 - 367 (UniProt: Q96T88)
| PDB | External Database | Details |
|---|---|---|
| Gly 293 | - | expression tag |
| Pro 294 | - | expression tag |
| Leu 295 | - | expression tag |
| Gly 296 | - | expression tag |
| Ser 297 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25263.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1094.7 | |
| All* | Total formula weight | 26357.9 |
