8XV4
Crystal structure of TTD-PHD domain of UHRF1 in complex with mStella peptide (residues 85-119)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase UHRF1 | polymer | 229 | 26456.9 | 2 | UniProt (Q96T88) Pfam (PF12148) Pfam (PF00628) | Homo sapiens (human) | Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,HuNp95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 2 | C, D (C, D) | Developmental pluripotency-associated protein 3 | polymer | 35 | 4299.2 | 2 | UniProt (Q8QZY3) | Mus musculus | Compaction-associated protein 1,Primordial germ cell protein 7,Stella |
| 3 | E, F, G, H, I... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B: 134 - 366 (UniProt: Q96T88)
| PDB | External Database | Details |
|---|---|---|
| Gly 129 | - | expression tag |
| Pro 130 | - | expression tag |
| Leu 131 | - | expression tag |
| Gly 132 | - | expression tag |
| Ser 133 | - | expression tag |
| - | Ser 165 | deletion |
| - | Arg 166 | deletion |
| - | Asp 167 | deletion |
| - | Glu 168 | deletion |
| - | Pro 169 | deletion |
| - | Cys 170 | deletion |
| - | Ser 171 | deletion |
| - | Ser 172 | deletion |
| - | Thr 173 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61512.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 457.9 | |
| All* | Total formula weight | 61970.0 |
