8XV4
Crystal structure of TTD-PHD domain of UHRF1 in complex with mStella peptide (residues 85-119)
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 62 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. CkhCkddvnrlcrvcachlcggrqdpdkq....................LmCde..Cdma.FHiyCldpplssvpsede................................WyCpeC |
| Chain | Residue | Details |
| A | CYS302-CYS363 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 112 |
| Details | ZN_FING: PHD-type => ECO:0000255|PROSITE-ProRule:PRU00146 |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Histone H3K4me0 binding |
| Chain | Residue | Details |
| A | GLN325 | |
| B | GLN325 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Histone H3R2me0 binding |
| Chain | Residue | Details |
| A | CYS336 | |
| A | ALA339 | |
| B | CYS336 | |
| B | ALA339 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8VDF2 |
| Chain | Residue | Details |
| A | SER165 | |
| B | SER165 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | ARG296 | |
| B | ARG296 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:15178447, ECO:0000269|PubMed:22837395 |
| Chain | Residue | Details |
| A | ASP307 | |
| B | ASP307 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | PRO288 | |
| B | PRO288 |
