8XOQ

Human Calcium and Integrin Binding Protein 2 (CIB2) Fusion to TMC1 CBD-1 domain at 2.4 Angstroms resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transmembrane channel-like protein 1,Calcium and integrin-binding family member 2	polymer	250	28686.8	2	UniProt (Q8TDI8) UniProt (O75838)	Homo sapiens (human)	Transmembrane cochlear-expressed protein 1,Kinase-interacting protein 2,KIP 2
2	C, D, E, F (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	G, H (A, B)	water	water		18.0	88	Chemie (HOH)

Sequence modifications

A, B: 1 - 52 (UniProt: Q8TDI8)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 53	-	linker
Leu 54	-	linker
Val 55	-	linker
Pro 56	-	linker
Arg 57	-	linker
Gly 58	-	linker
Ser 59	-	linker

A, B: 60 - 246 (UniProt: O75838)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57373.6
Non-Polymers*	Number of molecules	4
	Total formula weight	97.2
All*	Total formula weight	57470.8

*Water molecules are not included.