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8XND

Crystal structure of serine hydroxymethyltransferase 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Serine hydroxymethyltransferase, cytosolicpolymer47251706.74UniProt (P34896)
Pfam (PF00464)
Homo sapiens (human)SHMT,Glycine hydroxymethyltransferase,Serine methylase
2E, F, G, H
(A, B, C, D)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.14Chemie (PLP)
Sequence modifications
A, B, C, D: 11 - 480 (UniProt: P34896)
PDBExternal DatabaseDetails
Gln 9-expression tag
Gly 10-expression tag
Ala 20Lys 20conflict
Ala 279Lys 279conflict
Ala 442Arg 442conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight206826.9
Non-Polymers*Number of molecules4
Total formula weight988.6
All*Total formula weight207815.4
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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