8XM5
Cryo-EM structure of SARS-CoV-2 Omicron EG.5 spike protein(6P), RBD-closed state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein | polymer | 1271 | 141066.8 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
2 | C, A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) |
Sequence modifications
A, B, C: 28 - 1208 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Met -15 | - | initiating methionine |
Gly -14 | - | expression tag |
Ile -13 | - | expression tag |
Leu -12 | - | expression tag |
Pro -11 | - | expression tag |
Ser -10 | - | expression tag |
Pro -9 | - | expression tag |
Gly -8 | - | expression tag |
Met -7 | - | expression tag |
Pro -6 | - | expression tag |
Ala -5 | - | expression tag |
Leu -4 | - | expression tag |
Leu -3 | - | expression tag |
Ser -2 | - | expression tag |
Leu -1 | - | expression tag |
Val 0 | - | expression tag |
Ser 1 | - | expression tag |
Leu 2 | - | expression tag |
Leu 3 | - | expression tag |
Ser 4 | - | expression tag |
Val 5 | - | expression tag |
Leu 6 | - | expression tag |
Leu 7 | - | expression tag |
Met 8 | - | expression tag |
Gly 9 | - | expression tag |
Cys 10 | - | expression tag |
Val 11 | - | expression tag |
Ala 12 | - | expression tag |
Glu 13 | - | expression tag |
Thr 14 | - | expression tag |
Gly 15 | - | expression tag |
Thr 16 | - | expression tag |
Gln 17 | - | expression tag |
Cys 18 | - | expression tag |
Val 19 | - | expression tag |
Asn 20 | - | expression tag |
Leu 21 | - | expression tag |
Ile 22 | - | expression tag |
Thr 23 | - | expression tag |
Arg 24 | - | expression tag |
Thr 25 | - | expression tag |
Gln 26 | - | expression tag |
Ser 27 | - | expression tag |
Ala 83 | Val 83 | variant |
Asp 142 | Gly 142 | variant |
- | Tyr 144 | deletion |
Gln 146 | His 146 | variant |
Glu 183 | Gln 183 | variant |
Glu 213 | Val 213 | variant |
Val 252 | Gly 252 | variant |
His 339 | Gly 339 | variant |
Thr 346 | Arg 346 | variant |
Ile 368 | Leu 368 | variant |
Phe 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Ala 376 | Thr 376 | variant |
Asn 405 | Asp 405 | variant |
Ser 408 | Arg 408 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Pro 445 | Val 445 | variant |
Ser 446 | Gly 446 | variant |
Leu 456 | Phe 456 | variant |
Lys 460 | Asn 460 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Pro 486 | Phe 486 | variant |
Ser 490 | Phe 490 | variant |
Arg 498 | Gln 498 | variant |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Gly 614 | Asp 614 | variant |
Tyr 655 | His 655 | variant |
Lys 679 | Asn 679 | variant |
His 681 | Pro 681 | variant |
Lys 764 | Asn 764 | variant |
Tyr 796 | Asp 796 | variant |
Pro 817 | Phe 817 | engineered mutation |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
His 954 | Gln 954 | variant |
Lys 969 | Asn 969 | variant |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Gly 1209 | - | expression tag |
Ser 1210 | - | expression tag |
Gly 1211 | - | expression tag |
Tyr 1212 | - | expression tag |
Ile 1213 | - | expression tag |
Pro 1214 | - | expression tag |
Glu 1215 | - | expression tag |
Ala 1216 | - | expression tag |
Pro 1217 | - | expression tag |
Arg 1218 | - | expression tag |
Asp 1219 | - | expression tag |
Gly 1220 | - | expression tag |
Gln 1221 | - | expression tag |
Ala 1222 | - | expression tag |
Tyr 1223 | - | expression tag |
Val 1224 | - | expression tag |
Arg 1225 | - | expression tag |
Lys 1226 | - | expression tag |
Asp 1227 | - | expression tag |
Gly 1228 | - | expression tag |
Glu 1229 | - | expression tag |
Trp 1230 | - | expression tag |
Val 1231 | - | expression tag |
Leu 1232 | - | expression tag |
Leu 1233 | - | expression tag |
Ser 1234 | - | expression tag |
Thr 1235 | - | expression tag |
Phe 1236 | - | expression tag |
Leu 1237 | - | expression tag |
Gly 1238 | - | expression tag |
Ser 1239 | - | expression tag |
Ala 1240 | - | expression tag |
Trp 1241 | - | expression tag |
Ser 1242 | - | expression tag |
His 1243 | - | expression tag |
Pro 1244 | - | expression tag |
Gln 1245 | - | expression tag |
Phe 1246 | - | expression tag |
Glu 1247 | - | expression tag |
Lys 1248 | - | expression tag |
His 1249 | - | expression tag |
His 1250 | - | expression tag |
His 1251 | - | expression tag |
His 1252 | - | expression tag |
His 1253 | - | expression tag |
His 1254 | - | expression tag |
His 1255 | - | expression tag |
His 1256 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 423200.3 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 5972.6 | |
All* | Total formula weight | 429172.9 |