8XH9
Human Cx36/GJD2 (Ala14 deletion mutant) gap junction channel prepared with mefloquine, showing no bound mefloquine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Gap junction delta-2 protein | polymer | 330 | 37305.8 | 12 | UniProt (Q9UKL4) Pfam (PF00029) | Homo sapiens (human) | Connexin-36,Cx36,Gap junction alpha-9 protein |
| 2 | AA, AB, BA, BB, CA... (C, I, D, J, E...) | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 677.9 | 60 | Chemie (MC3) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 321 (UniProt: Q9UKL4)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 14 | deletion |
| Ser 322 | - | linker |
| Arg 323 | - | linker |
| Asp 324 | - | expression tag |
| Tyr 325 | - | expression tag |
| Lys 326 | - | expression tag |
| Asp 327 | - | expression tag |
| Asp 328 | - | expression tag |
| Asp 329 | - | expression tag |
| Asp 330 | - | expression tag |
| Lys 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 447670.0 | |
| Non-Polymers* | Number of molecules | 60 |
| Total formula weight | 40676.0 | |
| All* | Total formula weight | 488346.0 |
