8XGT
Crystal structure of human secretory glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-hydroxyindolin-2-one
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (B, A, C, D, E...) | Glutaminyl-peptide cyclotransferase | polymer | 329 | 37557.4 | 12 | UniProt (Q16769) Pfam (PF04389) | Homo sapiens (human) | Glutaminyl cyclase,QC,sQC,Glutaminyl-tRNA cyclotransferase,Glutamyl cyclase,EC |
| 2 | AA, CA, EA, GA, IA... (H, I, J, K, L...) | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 3 | BA, DA, FA, HA, JA... (H, I, J, K, L...) | (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-oxidanyl-1~{H}-indol-2-one | non-polymer | 277.3 | 12 | Chemie (A1D48) | |||
| 4 | KA, LA (C, J) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 450688.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 4112.2 | |
| All* | Total formula weight | 454801.0 |
