8XGR
ETB-eGt complex bound to endothelin-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,eGt-alpha | polymer | 434 | 48998.8 | 1 | UniProt (P63212) Pfam (PF00631) Pfam (PF00503) UniProt (by SIFTS) (P04695) | Bos taurus (cattle) | G gamma-I |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 374 | 40470.1 | 1 | Pfam (PF00400) UniProt (by SIFTS) (P54311) | Rattus rattus | |
| 3 | C (N) | Camelid antibody VHH fragment | polymer | 161 | 17395.6 | 1 | Lama glama | ||
| 4 | D (R) | Endothelin receptor type B | polymer | 609 | 67492.2 | 1 | Pfam (PF00001) UniProt (by SIFTS) (P24530) | Homo sapiens (human) | |
| 5 | E (L) | Endothelin-1 | polymer | 21 | 2498.0 | 1 | UniProt (P05305) Pfam (PF00322) | Homo sapiens | Preproendothelin-1,PPET1 |
Sequence modifications
G: 1 - 71 (UniProt: P63212)
G: 81 - 434 (PDB: 8XGR)
| PDB | External Database | Details |
|---|---|---|
| Gly 72 | - | linker |
| Ser 73 | - | linker |
| Ala 74 | - | linker |
| Gly 75 | - | linker |
| Ser 76 | - | linker |
| Ala 77 | - | linker |
| Gly 78 | - | linker |
| Ser 79 | - | linker |
| Ala 80 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 176854.7 | |
| All* | Total formula weight | 176854.7 |
