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8XGC

Structure of yeast replisome associated with FACT and histone hexamer, Composite map

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(2)
DNA replication licensing factor MCM2polymer86898911.51UniProt (A0A6A5Q1S9)
Pfam (PF12619)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
UniProt (by SIFTS) (P29469)
Saccharomyces cerevisiae (brewer's yeast)
2B
(3)
DNA replication licensing factor MCM3polymer971107653.51UniProt (P24279)
Pfam (PF22207)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Saccharomyces cerevisiae (brewer's yeast)Minichromosome maintenance protein 3
3C
(4)
DNA replication licensing factor MCM4polymer933105138.41UniProt (P30665)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF21128)
Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 54
4D
(5)
Minichromosome maintenance protein 5polymer77586505.71UniProt (P29496)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF21933)
Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 46
5E
(6)
DNA replication licensing factor MCM6polymer1017113110.21UniProt (P53091)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
Pfam (PF18263)
Saccharomyces cerevisiae (brewer's yeast)Minichromosome maintenance protein 6
6F
(7)
DNA replication licensing factor MCM7polymer84595049.91UniProt (A0A8H4BTB2)
Pfam (PF14551)
Pfam (PF17207)
Pfam (PF00493)
Pfam (PF17855)
UniProt (by SIFTS) (P38132)
Saccharomyces cerevisiae (brewer's yeast)
7G
(8)
DNA polymerase epsilon catalytic subunit Apolymer2222255992.51UniProt (P21951)
Pfam (PF03104)
Pfam (PF22634)
Pfam (PF08490)
Pfam (PF22912)
Saccharomyces cerevisiae (brewer's yeast)3'-5' exodeoxyribonuclease,DNA polymerase II subunit A
8H
(9)
DNA polymerase epsilon subunit Bpolymer68978425.91UniProt (P24482)
Pfam (PF04042)
Saccharomyces cerevisiae (brewer's yeast)DNA polymerase II subunit 2
9I
(A)
DNA replication complex GINS protein PSF1polymer20824230.61UniProt (Q12488)
Pfam (PF05916)
Saccharomyces cerevisiae (brewer's yeast)Partner of Sld five 1
10J
(B)
DNA replication complex GINS protein PSF2polymer25129341.11Pfam (PF05916)
UniProt (by SIFTS) (P40359)
Saccharomyces cerevisiae (brewer's yeast)
11K
(C)
DNA replication complex GINS protein PSF3polymer19421977.11UniProt (Q12146)
Pfam (PF22466)
Pfam (PF05916)
Saccharomyces cerevisiae (brewer's yeast)Partner of Sld five 3
12L
(D)
DNA replication complex GINS protein SLD5polymer29433983.61UniProt (Q03406)
Pfam (PF05916)
Pfam (PF16922)
Saccharomyces cerevisiae (brewer's yeast)
13M
(E)
Cell division control protein 45polymer65074324.81UniProt (Q08032)
Pfam (PF02724)
Saccharomyces cerevisiae (brewer's yeast)
14N, O, P
(F, G, H)
DNA polymerase alpha-binding proteinpolymer927104543.43UniProt (Q01454)
Pfam (PF12341)
Pfam (PF20946)
Saccharomyces cerevisiae (brewer's yeast)Chromosome replication protein CHL15,Chromosome transmission fidelity protein 4,Protein POB1
15Q
(I)
Topoisomerase 1-associated factor 1polymer1238141296.91UniProt (P53840)
Pfam (PF04821)
Saccharomyces cerevisiae (brewer's yeast)
16R
(J)
Chromosome segregation in meiosis protein 3polymer31736402.61UniProt (Q04659)
Pfam (PF07962)
Saccharomyces cerevisiae (brewer's yeast)
17S
(K)
Mediator of replication checkpoint protein 1polymer1096124516.41UniProt (P25588)
Pfam (PF09444)
Saccharomyces cerevisiae (brewer's yeast)DNA replication checkpoint mediator MRC1
18T
(L)
FACT complex subunit SPT16polymer1035118777.01UniProt (P32558)
Pfam (PF14826)
Pfam (PF00557)
Pfam (PF08644)
Pfam (PF08512)
Pfam (PF21091)
Saccharomyces cerevisiae (brewer's yeast)Cell division control protein 68,Facilitates chromatin transcription complex subunit SPT16,Suppressor of Ty protein 16
19U
(M)
FACT complex subunit POB3polymer55263068.61UniProt (Q04636)
Pfam (PF17292)
Pfam (PF03531)
Pfam (PF21103)
Pfam (PF08512)
Saccharomyces cerevisiae (brewer's yeast)Facilitates chromatin transcription complex subunit POB3
20V, Z
(N, R)
Histone H3polymer13615391.02UniProt (A0A6A5Q536)
Pfam (PF00125)
UniProt (by SIFTS) (P61830)
Saccharomyces cerevisiae (brewer's yeast)
21AA, W
(O, S)
Histone H4polymer10311395.42UniProt (P02309)
Pfam (PF15511)
Saccharomyces cerevisiae (brewer's yeast)
22X
(P)
Histone H2A.1polymer13214013.21UniProt (P04911)
Pfam (PF00125)
Pfam (PF16211)
Saccharomyces cerevisiae (brewer's yeast)
23Y
(Q)
Histone H2B.2polymer13114264.31UniProt (P02294)
Pfam (PF00125)
Saccharomyces cerevisiae (brewer's yeast)
24BA
(X)
DNA (51-MER)polymer5115689.11Saccharomyces cerevisiae
25CA
(Y)
DNA (39-MER)polymer3911935.81Saccharomyces cerevisiae
26DA, GA, HA, JA, LA...
(2, 4, 5, 6, 7...)
ZINC IONnon-polymer65.47Chemie (ZN)
27EA, FA, IA, KA, MA
(2, 3, 5, 6, 7)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.25Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains29
Total formula weight2031811.6
Non-Polymers*Number of molecules12
Total formula weight2593.9
All*Total formula weight2034405.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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