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8XGC

Structure of yeast replisome associated with FACT and histone hexamer, Composite map

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
20000727biological_processdouble-strand break repair via break-induced replication
20003677molecular_functionDNA binding
20003682molecular_functionchromatin binding
20003688molecular_functionDNA replication origin binding
20003689molecular_functionDNA clamp loader activity
20003697molecular_functionsingle-stranded DNA binding
20004386molecular_functionhelicase activity
20005515molecular_functionprotein binding
20005524molecular_functionATP binding
20005634cellular_componentnucleus
20005654cellular_componentnucleoplasm
20005656cellular_componentnuclear pre-replicative complex
20005737cellular_componentcytoplasm
20006260biological_processDNA replication
20006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
20006268biological_processDNA unwinding involved in DNA replication
20006270biological_processDNA replication initiation
20006271biological_processDNA strand elongation involved in DNA replication
20006279biological_processpremeiotic DNA replication
20006338biological_processchromatin remodeling
20006974biological_processDNA damage response
20008270molecular_functionzinc ion binding
20009378molecular_functionfour-way junction helicase activity
20016787molecular_functionhydrolase activity
20016887molecular_functionATP hydrolysis activity
20017116molecular_functionsingle-stranded DNA helicase activity
20031261cellular_componentDNA replication preinitiation complex
20031298cellular_componentreplication fork protection complex
20032508biological_processDNA duplex unwinding
20036121molecular_functiondouble-stranded DNA helicase activity
20042555cellular_componentMCM complex
20043138molecular_function3'-5' DNA helicase activity
20043596cellular_componentnuclear replication fork
20046872molecular_functionmetal ion binding
20061749molecular_functionforked DNA-dependent helicase activity
20061775molecular_functioncohesin loader activity
20071162cellular_componentCMG complex
20140584molecular_functionchromatin extrusion motor activity
20140588biological_processchromatin looping
20140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
20140849molecular_functionATP-dependent H2AZ histone chaperone activity
21902975biological_processmitotic DNA replication initiation
21905775biological_processobsolete negative regulation of DNA helicase activity
21990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
30000727biological_processdouble-strand break repair via break-induced replication
30000781cellular_componentchromosome, telomeric region
30003677molecular_functionDNA binding
30003682molecular_functionchromatin binding
30003688molecular_functionDNA replication origin binding
30003689molecular_functionDNA clamp loader activity
30003697molecular_functionsingle-stranded DNA binding
30004386molecular_functionhelicase activity
30005515molecular_functionprotein binding
30005524molecular_functionATP binding
30005634cellular_componentnucleus
30005654cellular_componentnucleoplasm
30005656cellular_componentnuclear pre-replicative complex
30005737cellular_componentcytoplasm
30006260biological_processDNA replication
30006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
30006268biological_processDNA unwinding involved in DNA replication
30006270biological_processDNA replication initiation
30006271biological_processDNA strand elongation involved in DNA replication
30006279biological_processpremeiotic DNA replication
30009378molecular_functionfour-way junction helicase activity
30016787molecular_functionhydrolase activity
30016887molecular_functionATP hydrolysis activity
30017116molecular_functionsingle-stranded DNA helicase activity
30030466biological_processsilent mating-type cassette heterochromatin formation
30031261cellular_componentDNA replication preinitiation complex
30031298cellular_componentreplication fork protection complex
30031509biological_processsubtelomeric heterochromatin formation
30032508biological_processDNA duplex unwinding
30036121molecular_functiondouble-stranded DNA helicase activity
30042555cellular_componentMCM complex
30043596cellular_componentnuclear replication fork
30061749molecular_functionforked DNA-dependent helicase activity
30061775molecular_functioncohesin loader activity
30071162cellular_componentCMG complex
30140584molecular_functionchromatin extrusion motor activity
30140588biological_processchromatin looping
30140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
30140849molecular_functionATP-dependent H2AZ histone chaperone activity
31902975biological_processmitotic DNA replication initiation
31904931molecular_functionMCM complex binding
31990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
40000727biological_processdouble-strand break repair via break-induced replication
40003677molecular_functionDNA binding
40003678molecular_functionDNA helicase activity
40003688molecular_functionDNA replication origin binding
40003689molecular_functionDNA clamp loader activity
40003697molecular_functionsingle-stranded DNA binding
40004386molecular_functionhelicase activity
40005515molecular_functionprotein binding
40005524molecular_functionATP binding
40005634cellular_componentnucleus
40005654cellular_componentnucleoplasm
40005656cellular_componentnuclear pre-replicative complex
40005737cellular_componentcytoplasm
40006260biological_processDNA replication
40006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
40006268biological_processDNA unwinding involved in DNA replication
40006270biological_processDNA replication initiation
40006271biological_processDNA strand elongation involved in DNA replication
40006279biological_processpremeiotic DNA replication
40006338biological_processchromatin remodeling
40008270molecular_functionzinc ion binding
40009378molecular_functionfour-way junction helicase activity
40016787molecular_functionhydrolase activity
40016887molecular_functionATP hydrolysis activity
40017116molecular_functionsingle-stranded DNA helicase activity
40031261cellular_componentDNA replication preinitiation complex
40031298cellular_componentreplication fork protection complex
40032508biological_processDNA duplex unwinding
40033260biological_processnuclear DNA replication
40036121molecular_functiondouble-stranded DNA helicase activity
40042555cellular_componentMCM complex
40043138molecular_function3'-5' DNA helicase activity
40043596cellular_componentnuclear replication fork
40061749molecular_functionforked DNA-dependent helicase activity
40061775molecular_functioncohesin loader activity
40071162cellular_componentCMG complex
40097373cellular_componentMCM core complex
40140584molecular_functionchromatin extrusion motor activity
40140588biological_processchromatin looping
40140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
40140849molecular_functionATP-dependent H2AZ histone chaperone activity
41902975biological_processmitotic DNA replication initiation
41990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
50000727biological_processdouble-strand break repair via break-induced replication
50000781cellular_componentchromosome, telomeric region
50003677molecular_functionDNA binding
50003682molecular_functionchromatin binding
50003688molecular_functionDNA replication origin binding
50003689molecular_functionDNA clamp loader activity
50003697molecular_functionsingle-stranded DNA binding
50004386molecular_functionhelicase activity
50005515molecular_functionprotein binding
50005524molecular_functionATP binding
50005634cellular_componentnucleus
50005654cellular_componentnucleoplasm
50005656cellular_componentnuclear pre-replicative complex
50005737cellular_componentcytoplasm
50006260biological_processDNA replication
50006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
50006268biological_processDNA unwinding involved in DNA replication
50006270biological_processDNA replication initiation
50006279biological_processpremeiotic DNA replication
50006368biological_processtranscription elongation by RNA polymerase II
50008270molecular_functionzinc ion binding
50009378molecular_functionfour-way junction helicase activity
50016787molecular_functionhydrolase activity
50016887molecular_functionATP hydrolysis activity
50017116molecular_functionsingle-stranded DNA helicase activity
50030174biological_processregulation of DNA-templated DNA replication initiation
50031261cellular_componentDNA replication preinitiation complex
50031298cellular_componentreplication fork protection complex
50031507biological_processheterochromatin formation
50031509biological_processsubtelomeric heterochromatin formation
50032508biological_processDNA duplex unwinding
50033260biological_processnuclear DNA replication
50036121molecular_functiondouble-stranded DNA helicase activity
50042555cellular_componentMCM complex
50043138molecular_function3'-5' DNA helicase activity
50043596cellular_componentnuclear replication fork
50061749molecular_functionforked DNA-dependent helicase activity
50061775molecular_functioncohesin loader activity
50071162cellular_componentCMG complex
50140584molecular_functionchromatin extrusion motor activity
50140588biological_processchromatin looping
50140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
50140849molecular_functionATP-dependent H2AZ histone chaperone activity
51990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
60000727biological_processdouble-strand break repair via break-induced replication
60003677molecular_functionDNA binding
60003678molecular_functionDNA helicase activity
60003688molecular_functionDNA replication origin binding
60003689molecular_functionDNA clamp loader activity
60003697molecular_functionsingle-stranded DNA binding
60004386molecular_functionhelicase activity
60005515molecular_functionprotein binding
60005524molecular_functionATP binding
60005634cellular_componentnucleus
60005654cellular_componentnucleoplasm
60005656cellular_componentnuclear pre-replicative complex
60005737cellular_componentcytoplasm
60006260biological_processDNA replication
60006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
60006268biological_processDNA unwinding involved in DNA replication
60006270biological_processDNA replication initiation
60006271biological_processDNA strand elongation involved in DNA replication
60006279biological_processpremeiotic DNA replication
60006338biological_processchromatin remodeling
60008270molecular_functionzinc ion binding
60009378molecular_functionfour-way junction helicase activity
60016787molecular_functionhydrolase activity
60016887molecular_functionATP hydrolysis activity
60017116molecular_functionsingle-stranded DNA helicase activity
60031261cellular_componentDNA replication preinitiation complex
60031298cellular_componentreplication fork protection complex
60032508biological_processDNA duplex unwinding
60036121molecular_functiondouble-stranded DNA helicase activity
60042555cellular_componentMCM complex
60043138molecular_function3'-5' DNA helicase activity
60043596cellular_componentnuclear replication fork
60061749molecular_functionforked DNA-dependent helicase activity
60061775molecular_functioncohesin loader activity
60071162cellular_componentCMG complex
60097373cellular_componentMCM core complex
60140584molecular_functionchromatin extrusion motor activity
60140588biological_processchromatin looping
60140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
60140849molecular_functionATP-dependent H2AZ histone chaperone activity
61902969biological_processmitotic DNA replication
61990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
70000727biological_processdouble-strand break repair via break-induced replication
70000781cellular_componentchromosome, telomeric region
70003677molecular_functionDNA binding
70003678molecular_functionDNA helicase activity
70003682molecular_functionchromatin binding
70003688molecular_functionDNA replication origin binding
70003689molecular_functionDNA clamp loader activity
70003697molecular_functionsingle-stranded DNA binding
70004386molecular_functionhelicase activity
70005515molecular_functionprotein binding
70005524molecular_functionATP binding
70005634cellular_componentnucleus
70005654cellular_componentnucleoplasm
70005656cellular_componentnuclear pre-replicative complex
70005737cellular_componentcytoplasm
70006260biological_processDNA replication
70006267biological_processpre-replicative complex assembly involved in nuclear cell cycle DNA replication
70006268biological_processDNA unwinding involved in DNA replication
70006270biological_processDNA replication initiation
70006271biological_processDNA strand elongation involved in DNA replication
70006279biological_processpremeiotic DNA replication
70008270molecular_functionzinc ion binding
70009378molecular_functionfour-way junction helicase activity
70016787molecular_functionhydrolase activity
70016887molecular_functionATP hydrolysis activity
70017116molecular_functionsingle-stranded DNA helicase activity
70030466biological_processsilent mating-type cassette heterochromatin formation
70031261cellular_componentDNA replication preinitiation complex
70031298cellular_componentreplication fork protection complex
70031509biological_processsubtelomeric heterochromatin formation
70032508biological_processDNA duplex unwinding
70033260biological_processnuclear DNA replication
70036121molecular_functiondouble-stranded DNA helicase activity
70042555cellular_componentMCM complex
70043138molecular_function3'-5' DNA helicase activity
70043596cellular_componentnuclear replication fork
70061749molecular_functionforked DNA-dependent helicase activity
70061775molecular_functioncohesin loader activity
70071162cellular_componentCMG complex
70097373cellular_componentMCM core complex
70140584molecular_functionchromatin extrusion motor activity
70140588biological_processchromatin looping
70140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
70140849molecular_functionATP-dependent H2AZ histone chaperone activity
71904931molecular_functionMCM complex binding
71990518molecular_functionsingle-stranded 3'-5' DNA helicase activity
80000166molecular_functionnucleotide binding
80000278biological_processmitotic cell cycle
80003676molecular_functionnucleic acid binding
80003677molecular_functionDNA binding
80003690molecular_functiondouble-stranded DNA binding
80003697molecular_functionsingle-stranded DNA binding
80003729molecular_functionmRNA binding
80003887molecular_functionDNA-directed DNA polymerase activity
80005515molecular_functionprotein binding
80005634cellular_componentnucleus
80005657cellular_componentreplication fork
80006260biological_processDNA replication
80006261biological_processDNA-templated DNA replication
80006272biological_processleading strand elongation
80006281biological_processDNA repair
80006284biological_processbase-excision repair
80006287biological_processbase-excision repair, gap-filling
80006297biological_processnucleotide-excision repair, DNA gap filling
80006302biological_processdouble-strand break repair
80006303biological_processdouble-strand break repair via nonhomologous end joining
80007064biological_processmitotic sister chromatid cohesion
80008270molecular_functionzinc ion binding
80008310molecular_functionsingle-stranded DNA 3'-5' DNA exonuclease activity
80008622cellular_componentepsilon DNA polymerase complex
80016787molecular_functionhydrolase activity
80031573biological_processmitotic intra-S DNA damage checkpoint signaling
80032183molecular_functionSUMO binding
80033314biological_processmitotic DNA replication checkpoint signaling
80034061molecular_functionDNA polymerase activity
80035822biological_processgene conversion
80042276biological_processerror-prone translesion synthesis
80043231cellular_componentintracellular membrane-bounded organelle
80043596cellular_componentnuclear replication fork
80045004biological_processDNA replication proofreading
80046872molecular_functionmetal ion binding
80051539molecular_function4 iron, 4 sulfur cluster binding
90003677molecular_functionDNA binding
90003690molecular_functiondouble-stranded DNA binding
90003697molecular_functionsingle-stranded DNA binding
90003887molecular_functionDNA-directed DNA polymerase activity
90005515molecular_functionprotein binding
90005634cellular_componentnucleus
90005694cellular_componentchromosome
90005737cellular_componentcytoplasm
90006260biological_processDNA replication
90006261biological_processDNA-templated DNA replication
90008622cellular_componentepsilon DNA polymerase complex
90030337molecular_functionDNA polymerase processivity factor activity
90031981cellular_componentnuclear lumen
90042276biological_processerror-prone translesion synthesis
90043596cellular_componentnuclear replication fork
90045005biological_processDNA-templated DNA replication maintenance of fidelity
A0000727biological_processdouble-strand break repair via break-induced replication
A0000811cellular_componentGINS complex
A0003674molecular_functionmolecular_function
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006268biological_processDNA unwinding involved in DNA replication
A0031261cellular_componentDNA replication preinitiation complex
A0031298cellular_componentreplication fork protection complex
A0043596cellular_componentnuclear replication fork
A0071162cellular_componentCMG complex
A1902983biological_processDNA strand elongation involved in mitotic DNA replication
B0000228cellular_componentnuclear chromosome
B0000727biological_processdouble-strand break repair via break-induced replication
B0000811cellular_componentGINS complex
B0003674molecular_functionmolecular_function
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0006260biological_processDNA replication
B0006261biological_processDNA-templated DNA replication
B0006268biological_processDNA unwinding involved in DNA replication
B0031261cellular_componentDNA replication preinitiation complex
B0031298cellular_componentreplication fork protection complex
B0043596cellular_componentnuclear replication fork
B0071162cellular_componentCMG complex
C0000727biological_processdouble-strand break repair via break-induced replication
C0000811cellular_componentGINS complex
C0003674molecular_functionmolecular_function
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0006260biological_processDNA replication
C0006261biological_processDNA-templated DNA replication
C0006268biological_processDNA unwinding involved in DNA replication
C0031261cellular_componentDNA replication preinitiation complex
C0031298cellular_componentreplication fork protection complex
C0043596cellular_componentnuclear replication fork
C0071162cellular_componentCMG complex
C1902975biological_processmitotic DNA replication initiation
D0000727biological_processdouble-strand break repair via break-induced replication
D0000811cellular_componentGINS complex
D0003674molecular_functionmolecular_function
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0006260biological_processDNA replication
D0006261biological_processDNA-templated DNA replication
D0006268biological_processDNA unwinding involved in DNA replication
D0031261cellular_componentDNA replication preinitiation complex
D0031298cellular_componentreplication fork protection complex
D0043596cellular_componentnuclear replication fork
D0071162cellular_componentCMG complex
E0000727biological_processdouble-strand break repair via break-induced replication
E0003682molecular_functionchromatin binding
E0003688molecular_functionDNA replication origin binding
E0003697molecular_functionsingle-stranded DNA binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0006260biological_processDNA replication
E0006268biological_processDNA unwinding involved in DNA replication
E0006270biological_processDNA replication initiation
E0031261cellular_componentDNA replication preinitiation complex
E0031298cellular_componentreplication fork protection complex
E0043596cellular_componentnuclear replication fork
E0071162cellular_componentCMG complex
E1902977biological_processmitotic DNA replication preinitiation complex assembly
F0000228cellular_componentnuclear chromosome
F0000278biological_processmitotic cell cycle
F0000727biological_processdouble-strand break repair via break-induced replication
F0003682molecular_functionchromatin binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0006260biological_processDNA replication
F0006261biological_processDNA-templated DNA replication
F0006270biological_processDNA replication initiation
F0006281biological_processDNA repair
F0006334biological_processnucleosome assembly
F0007064biological_processmitotic sister chromatid cohesion
F0031298cellular_componentreplication fork protection complex
F0034085biological_processestablishment of sister chromatid cohesion
F0035361cellular_componentCul8-RING ubiquitin ligase complex
F0042802molecular_functionidentical protein binding
F0043596cellular_componentnuclear replication fork
G0000228cellular_componentnuclear chromosome
G0000278biological_processmitotic cell cycle
G0000727biological_processdouble-strand break repair via break-induced replication
G0003682molecular_functionchromatin binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0006260biological_processDNA replication
G0006261biological_processDNA-templated DNA replication
G0006270biological_processDNA replication initiation
G0006281biological_processDNA repair
G0006334biological_processnucleosome assembly
G0007064biological_processmitotic sister chromatid cohesion
G0031298cellular_componentreplication fork protection complex
G0034085biological_processestablishment of sister chromatid cohesion
G0035361cellular_componentCul8-RING ubiquitin ligase complex
G0042802molecular_functionidentical protein binding
G0043596cellular_componentnuclear replication fork
H0000228cellular_componentnuclear chromosome
H0000278biological_processmitotic cell cycle
H0000727biological_processdouble-strand break repair via break-induced replication
H0003682molecular_functionchromatin binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0006260biological_processDNA replication
H0006261biological_processDNA-templated DNA replication
H0006270biological_processDNA replication initiation
H0006281biological_processDNA repair
H0006334biological_processnucleosome assembly
H0007064biological_processmitotic sister chromatid cohesion
H0031298cellular_componentreplication fork protection complex
H0034085biological_processestablishment of sister chromatid cohesion
H0035361cellular_componentCul8-RING ubiquitin ligase complex
H0042802molecular_functionidentical protein binding
H0043596cellular_componentnuclear replication fork
I0000076biological_processDNA replication checkpoint signaling
I0003674molecular_functionmolecular_function
I0003677molecular_functionDNA binding
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005829cellular_componentcytosol
I0006260biological_processDNA replication
I0006281biological_processDNA repair
I0007064biological_processmitotic sister chromatid cohesion
I0008156biological_processnegative regulation of DNA replication
I0031297biological_processreplication fork processing
I0031298cellular_componentreplication fork protection complex
I0043111biological_processreplication fork arrest
I0043570biological_processmaintenance of DNA repeat elements
I0043596cellular_componentnuclear replication fork
I0051321biological_processmeiotic cell cycle
J0000076biological_processDNA replication checkpoint signaling
J0003674molecular_functionmolecular_function
J0003677molecular_functionDNA binding
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0006281biological_processDNA repair
J0006974biological_processDNA damage response
J0007064biological_processmitotic sister chromatid cohesion
J0008156biological_processnegative regulation of DNA replication
J0031297biological_processreplication fork processing
J0031298cellular_componentreplication fork protection complex
J0034087biological_processestablishment of mitotic sister chromatid cohesion
J0043111biological_processreplication fork arrest
J0043570biological_processmaintenance of DNA repeat elements
J0043596cellular_componentnuclear replication fork
J0045132biological_processmeiotic chromosome segregation
J0051321biological_processmeiotic cell cycle
K0000076biological_processDNA replication checkpoint signaling
K0000723biological_processtelomere maintenance
K0000781cellular_componentchromosome, telomeric region
K0003674molecular_functionmolecular_function
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0006260biological_processDNA replication
K0006281biological_processDNA repair
K0007064biological_processmitotic sister chromatid cohesion
K0007095biological_processmitotic G2 DNA damage checkpoint signaling
K0010997molecular_functionanaphase-promoting complex binding
K0030466biological_processsilent mating-type cassette heterochromatin formation
K0031297biological_processreplication fork processing
K0031298cellular_componentreplication fork protection complex
K0031509biological_processsubtelomeric heterochromatin formation
K0031573biological_processmitotic intra-S DNA damage checkpoint signaling
K0033262biological_processregulation of nuclear cell cycle DNA replication
K0033314biological_processmitotic DNA replication checkpoint signaling
K0034399cellular_componentnuclear periphery
K0043570biological_processmaintenance of DNA repeat elements
K0043596cellular_componentnuclear replication fork
K0050821biological_processprotein stabilization
K0071470biological_processcellular response to osmotic stress
L0000785cellular_componentchromatin
L0003682molecular_functionchromatin binding
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005694cellular_componentchromosome
L0006260biological_processDNA replication
L0006261biological_processDNA-templated DNA replication
L0006281biological_processDNA repair
L0006325biological_processchromatin organization
L0006334biological_processnucleosome assembly
L0006368biological_processtranscription elongation by RNA polymerase II
L0007063biological_processregulation of sister chromatid cohesion
L0031298cellular_componentreplication fork protection complex
L0031491molecular_functionnucleosome binding
L0034728biological_processnucleosome organization
L0035101cellular_componentFACT complex
L0042393molecular_functionhistone binding
L0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
L0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
L1902275biological_processregulation of chromatin organization
M0000785cellular_componentchromatin
M0003677molecular_functionDNA binding
M0003682molecular_functionchromatin binding
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005694cellular_componentchromosome
M0006260biological_processDNA replication
M0006261biological_processDNA-templated DNA replication
M0006281biological_processDNA repair
M0006325biological_processchromatin organization
M0031298cellular_componentreplication fork protection complex
M0031491molecular_functionnucleosome binding
M0034728biological_processnucleosome organization
M0035101cellular_componentFACT complex
M0042393molecular_functionhistone binding
M0045899biological_processpositive regulation of RNA polymerase II transcription preinitiation complex assembly
M1902275biological_processregulation of chromatin organization
N0000500cellular_componentRNA polymerase I upstream activating factor complex
N0000786cellular_componentnucleosome
N0003677molecular_functionDNA binding
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005694cellular_componentchromosome
N0006325biological_processchromatin organization
N0006355biological_processregulation of DNA-templated transcription
N0006878biological_processintracellular copper ion homeostasis
N0008823molecular_functioncupric reductase (NADH) activity
N0009060biological_processaerobic respiration
N0009303biological_processrRNA transcription
N0030527molecular_functionstructural constituent of chromatin
N0031298cellular_componentreplication fork protection complex
N0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
N0043505cellular_componentCENP-A containing nucleosome
N0043935biological_processsexual sporulation resulting in formation of a cellular spore
N0045943biological_processpositive regulation of transcription by RNA polymerase I
N0046982molecular_functionprotein heterodimerization activity
N0070911biological_processglobal genome nucleotide-excision repair
O0000500cellular_componentRNA polymerase I upstream activating factor complex
O0000786cellular_componentnucleosome
O0003677molecular_functionDNA binding
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005694cellular_componentchromosome
O0006325biological_processchromatin organization
O0006334biological_processnucleosome assembly
O0006355biological_processregulation of DNA-templated transcription
O0030527molecular_functionstructural constituent of chromatin
O0031298cellular_componentreplication fork protection complex
O0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
O0042802molecular_functionidentical protein binding
O0045943biological_processpositive regulation of transcription by RNA polymerase I
O0046982molecular_functionprotein heterodimerization activity
P0000122biological_processnegative regulation of transcription by RNA polymerase II
P0000786cellular_componentnucleosome
P0003677molecular_functionDNA binding
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005694cellular_componentchromosome
P0006281biological_processDNA repair
P0006325biological_processchromatin organization
P0030527molecular_functionstructural constituent of chromatin
P0031298cellular_componentreplication fork protection complex
P0031507biological_processheterochromatin formation
P0046982molecular_functionprotein heterodimerization activity
Q0000786cellular_componentnucleosome
Q0003677molecular_functionDNA binding
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005694cellular_componentchromosome
Q0006325biological_processchromatin organization
Q0006355biological_processregulation of DNA-templated transcription
Q0030527molecular_functionstructural constituent of chromatin
Q0031298cellular_componentreplication fork protection complex
Q0046982molecular_functionprotein heterodimerization activity
R0000500cellular_componentRNA polymerase I upstream activating factor complex
R0000786cellular_componentnucleosome
R0003677molecular_functionDNA binding
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005694cellular_componentchromosome
R0006325biological_processchromatin organization
R0006355biological_processregulation of DNA-templated transcription
R0006878biological_processintracellular copper ion homeostasis
R0008823molecular_functioncupric reductase (NADH) activity
R0009060biological_processaerobic respiration
R0009303biological_processrRNA transcription
R0030527molecular_functionstructural constituent of chromatin
R0031298cellular_componentreplication fork protection complex
R0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
R0043505cellular_componentCENP-A containing nucleosome
R0043935biological_processsexual sporulation resulting in formation of a cellular spore
R0045943biological_processpositive regulation of transcription by RNA polymerase I
R0046982molecular_functionprotein heterodimerization activity
R0070911biological_processglobal genome nucleotide-excision repair
S0000500cellular_componentRNA polymerase I upstream activating factor complex
S0000786cellular_componentnucleosome
S0003677molecular_functionDNA binding
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005694cellular_componentchromosome
S0006325biological_processchromatin organization
S0006334biological_processnucleosome assembly
S0006355biological_processregulation of DNA-templated transcription
S0030527molecular_functionstructural constituent of chromatin
S0031298cellular_componentreplication fork protection complex
S0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
S0042802molecular_functionidentical protein binding
S0045943biological_processpositive regulation of transcription by RNA polymerase I
S0046982molecular_functionprotein heterodimerization activity
Functional Information from PROSITE/UniProt
site_idPS00014
Number of Residues4
DetailsER_TARGET Endoplasmic reticulum targeting sequence. SQEL
ChainResidueDetails
PSER129-LEU132

site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLtFPV
ChainResidueDetails
PALA23-VAL29

site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
SGLY15-HIS19

site_idPS00322
Number of Residues7
DetailsHISTONE_H3_1 Histone H3 signature 1. KAPRKQL
ChainResidueDetails
NLYS15-LEU21

site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVSEG
ChainResidueDetails
QARG96-GLY118

site_idPS00847
Number of Residues9
DetailsMCM_1 MCM family signature. GVCCIDEFD
ChainResidueDetails
4GLY627-ASP635
6GLY634-ASP642
2GLY602-ASP610
5GLY475-ASP483
3GLY468-ASP476
7GLY519-ASP527

site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
ChainResidueDetails
NPRO67-ILE75

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11742990, ECO:0000269|PubMed:11751634, ECO:0000269|PubMed:11752412, ECO:0000269|PubMed:12152067, ECO:0000269|PubMed:12353038, ECO:0000269|PubMed:12845608, ECO:0000269|PubMed:15949446, ECO:0000269|PubMed:16122352, ECO:0000269|PubMed:16168379, ECO:0000269|PubMed:16185711, ECO:0000269|PubMed:17194708
ChainResidueDetails
NLYS5
RLYS5
7ALA465
7LYS466
7SER467
7ASN568
7ARG593
7ARG687

site_idSWS_FT_FI2
Number of Residues6
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:17194708
ChainResidueDetails
NLYS10
NLYS19
NLYS28
RLYS10
RLYS19
RLYS28
8CYS2179
8CYS2181

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:10911986, ECO:0000269|PubMed:10975519, ECO:0000269|PubMed:15719021
ChainResidueDetails
NSER11
RSER11
2SER23
2SER164
2SER170
HTHR411

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-butyryllysine; alternate => ECO:0000269|PubMed:19113941, ECO:0000269|PubMed:27105113
ChainResidueDetails
NLYS15
RLYS15
SLYS32
SLYS78

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: N6-propionyllysine; alternate => ECO:0000269|PubMed:19113941
ChainResidueDetails
NLYS24
NLYS57
RLYS24
RLYS57

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11839797, ECO:0000269|PubMed:12152067, ECO:0000269|PubMed:12629047, ECO:0000269|PubMed:12773564, ECO:0000269|PubMed:12917322, ECO:0000269|PubMed:15798214, ECO:0000269|PubMed:17194708, ECO:0000269|PubMed:19113941
ChainResidueDetails
NLYS37
RLYS37

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:19113941
ChainResidueDetails
NLYS38
RLYS38

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:17194708
ChainResidueDetails
NLYS65
RLYS65

site_idSWS_FT_FI9
Number of Residues2
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
ChainResidueDetails
NLYS80
RLYS80

site_idSWS_FT_FI10
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternate
ChainResidueDetails
QLYS7
QLYS8

site_idSWS_FT_FI11
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549
ChainResidueDetails
QLYS124

site_idSWS_FT_FI12
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternate => ECO:0000305
ChainResidueDetails
QLYS17
QLYS18

227561

PDB entries from 2024-11-20

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