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8XER

Cryo-EM structure of integrin ITGAV, ITGB3 and Cilengitide TFA complex, conformation 1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Integrin alpha-Vpolymer1048116155.41UniProt (P06756)
Pfam (PF01839)
Pfam (PF08441)
Pfam (PF20805)
Pfam (PF20806)
Pfam (PF00357)
Homo sapiens (human)
2B
(B)
Integrin beta-3polymer78887150.81UniProt (P05106)
Pfam (PF18372)
Pfam (PF07974)
Pfam (PF07965)
Pfam (PF08725)
Pfam (PF17205)
Pfam (PF00362)
Homo sapiens (human)
3C
(B)
2-[(2~{R},5~{R},8~{S},11~{S})-11-(3-carbamimidamidopropyl)-7-methyl-3,6,9,12,15-pentakis(oxidanylidene)-5-(phenylmethyl)-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]ethanoic acidnon-polymer588.71Chemie (A1LU4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight203306.2
Non-Polymers*Number of molecules1
Total formula weight588.7
All*Total formula weight203894.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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