8XC4

Nipah virus attachment glycoprotein head domain in complex with a broadly neutralizing antibody 1E5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Glycoprotein	polymer	439	49310.7	2	UniProt (Q4VCP5) Pfam (PF00423) In PDB	Henipavirus nipahense
2	C, E	1E5-VH	polymer	242	26120.0	2		Macaca mulatta
3	D, F	1E5-VL	polymer	214	23235.8	2		Macaca mulatta
4	G	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
5	H, K	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	2	In PDB GlyTouCan (G42466VF)
6	I, L	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
7	J	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		878.8	1	In PDB GlyTouCan (G92953ND)
8	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

A, B: 176 - 602 (UniProt: Q4VCP5)

PDB	External Database	Details
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
Gly 170	-	expression tag
Ser 171	-	expression tag
Gly 172	-	expression tag
Gly 173	-	expression tag
Gly 174	-	expression tag
Ser 175	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	197333.1
Branched	Number of molecules	6
	Total formula weight	4574.2
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	202349.7

*Water molecules are not included.