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8XBM

Structure of Cx43/GJA1 gap junction intercellular channel in complex with diC8-PIP2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Gap junction alpha-1 proteinpolymer25729291.412UniProt (P17302)
Pfam (PF00029)
Homo sapiens (human)Connexin-43,Cx43,Gap junction 43 kDa heart protein
2M, N, O, P, Q...
(A, B, C, D, E...)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.612Chemie (PIO)
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 2 - 257 (UniProt: P17302)
PDBExternal DatabaseDetails
Ace 1-acetylation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight351496.6
Non-Polymers*Number of molecules12
Total formula weight8958.8
All*Total formula weight360455.4
*Water molecules are not included.

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PDB entries from 2026-02-25

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