8X46

Crystal structure of DIMT1 in complex with adenosylornithine (SFG) from Pyrococcus horikoshii

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable ribosomal RNA small subunit methyltransferase A	polymer	290	33365.1	2	UniProt (O59487) Pfam (PF00398)	Pyrococcus horikoshii OT3
2	C, L (A, B)	SINEFUNGIN	non-polymer		381.4	2	Chemie (SFG)
3	D, E, F, G, H... (A, B)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
4	I, N (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	J, Q (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	K, R (A, B)	ARGININE	non-polymer		175.2	2	Chemie (ARG)
7	O (B)	SULFITE ION	non-polymer		80.1	1	Chemie (SO3)
8	P (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
9	S, T (A, B)	water	water		18.0	235	Chemie (HOH)

Sequence modifications

A, B: 23 - 290 (UniProt: O59487)

PDB	External Database	Details
Met 1	-	initiating methionine
Ser 2	-	expression tag
Ser 3	-	expression tag
Arg 4	-	expression tag
Ile 5	-	expression tag
Arg 6	-	expression tag
Ile 7	-	expression tag
Asn 8	-	expression tag
Thr 9	-	expression tag
Lys 10	-	expression tag
Ser 11	-	expression tag
Leu 12	-	expression tag
Leu 13	-	expression tag
Val 14	-	expression tag
Gln 15	-	expression tag
Pro 16	-	expression tag
Gly 17	-	expression tag
Tyr 18	-	expression tag
Ser 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Lys 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66730.2
Non-Polymers*	Number of molecules	16
	Total formula weight	1930.9
All*	Total formula weight	68661.2

*Water molecules are not included.