8WX4

Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Solute carrier family 15 member 4	polymer	600	64856.2	2	UniProt (Q8N697) Pfam (PF00854)	Homo sapiens (human)
2	C, E (B, A)	LYSINE	non-polymer		147.2	2	Chemie (LYS)
3	D, F (B, A)	LEUCINE	non-polymer		131.2	2	Chemie (LEU)

Sequence modifications

B, A: 1 - 577 (UniProt: Q8N697)

PDB	External Database	Details
Gly 578	-	expression tag
Ser 579	-	expression tag
Ile 580	-	expression tag
Glu 581	-	expression tag
Gly 582	-	expression tag
Arg 583	-	expression tag
Ile 584	-	expression tag
Val 585	-	expression tag
Lys 586	-	expression tag
Asp 587	-	expression tag
Tyr 588	-	expression tag
Lys 589	-	expression tag
Asp 590	-	expression tag
Asp 591	-	expression tag
Asp 592	-	expression tag
Asp 593	-	expression tag
Lys 594	-	expression tag
His 595	-	expression tag
His 596	-	expression tag
His 597	-	expression tag
His 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	129712.4
Non-Polymers*	Number of molecules	4
	Total formula weight	556.7
All*	Total formula weight	130269.1

*Water molecules are not included.