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8WUU

SpCas9-pegRNA-target DNA complex (pre-initiation)

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CRISPR-associated endonuclease Cas9/Csn1polymer1367158457.61UniProt (Q99ZW2)
Pfam (PF16593)
Pfam (PF16592)
Pfam (PF13395)
Pfam (PF22702)
Pfam (PF16595)
Streptococcus pyogenes serotype M1
2B
(C)
DNA (51-MER)polymer5115636.01Streptococcus pyogenes
3C
(D)
DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3')polymer175291.41Streptococcus pyogenes
4D
(B)
RNA (137-MER)polymer13744300.41Streptococcus pyogenes
5E
(F)
DNA (34-MER)polymer3410462.71Streptococcus pyogenes
Sequence modifications
A: 2 - 1368 (UniProt: Q99ZW2)
PDBExternal DatabaseDetails
Ala 10Asp 10engineered mutation
Ala 840His 840engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight234148.2
All*Total formula weight234148.2
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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