8WUL
Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (C, A, E, G) | TCR alpha chain | polymer | 198 | 22105.7 | 4 | Pfam (PF07686) Pfam (PF09291) UniProt (by SIFTS) (Q5R1I3) UniProt (by SIFTS) (P01849) | Mus musculus | |
| 2 | B, D, F, H (D, B, F, H) | TCR beta chain | polymer | 239 | 27321.8 | 4 | Mus musculus | ||
| 3 | I, L, O, R (L, I, O, R) | MHC class I antigen | polymer | 274 | 31725.9 | 4 | UniProt (A0A6M6CC39) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (A0A583ZB34) | Homo sapiens (human) | HLA-A*1101 |
| 4 | J, M, P, S (M, J, P, S) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 4 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 5 | K, N, Q, T (N, K, Q, T) | KRAS-G12V nonamer peptide | polymer | 9 | 786.0 | 4 | UniProt (by SIFTS) (P01116) | Homo sapiens | |
| 6 | AA, BA, CA, DA, EA... (G, H, L, M, N...) | water | water | 18.0 | 403 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 374749.9 | |
| All* | Total formula weight | 374749.9 |
