8WTR
HUMAN SQUALENE SYNTHASE IN COMPLEX WITH (1S,3R)-3-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6,8-dioxo-5,6,7,8,10,11-hexahydro-13H-12-oxa-5,9-diaza-benzocycloundecen-9-yl]-cyclohexanecarboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Squalene synthase | polymer | 340 | 39166.7 | 1 | UniProt (P37268) Pfam (PF00494) | Homo sapiens (human) | SQS,SS,FPP:FPP farnesyltransferase,Farnesyl-diphosphate farnesyltransferase,Farnesyl-diphosphate farnesyltransferase 1 |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | (1~{S},3~{R})-3-[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3,5-bis(oxidanylidene)-9-oxa-2,6-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-6-yl]cyclohexane-1-carboxylic acid | non-polymer | 571.1 | 1 | Chemie (KV3) | |||
| 4 | D (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39166.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 666.1 | |
| All* | Total formula weight | 39832.8 |
