8WTQ
HUMAN SQUALENE SYNTHASE IN COMPLEX WITH {1-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6-oxo-6,7,10,11-tetrahydro-5H,9H,13H-12-oxa-5,8-diaza-benzocycloundecene-8-carbonyl]-piperidin-4-yl}-acetic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Squalene synthase | polymer | 340 | 39166.7 | 1 | UniProt (P37268) Pfam (PF00494) In PDB | Homo sapiens (human) | SQS,SS,FPP:FPP farnesyltransferase,Farnesyl-diphosphate farnesyltransferase,Farnesyl-diphosphate farnesyltransferase 1 |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
3 | A | 2-[1-[[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3-oxidanylidene-9-oxa-2,5-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-5-yl]carbonyl]piperidin-4-yl]ethanoic acid | non-polymer | 600.1 | 1 | Chemie (KUO) | |||
4 | water | water | 18.0 | 324 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39166.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 695.1 | |
All* | Total formula weight | 39861.8 |