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8WTQ

HUMAN SQUALENE SYNTHASE IN COMPLEX WITH {1-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6-oxo-6,7,10,11-tetrahydro-5H,9H,13H-12-oxa-5,8-diaza-benzocycloundecene-8-carbonyl]-piperidin-4-yl}-acetic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASqualene synthasepolymer34039166.71UniProt (P37268)
Pfam (PF00494)
In PDB
Homo sapiens (human)SQS,SS,FPP:FPP farnesyltransferase,Farnesyl-diphosphate farnesyltransferase,Farnesyl-diphosphate farnesyltransferase 1
2APHOSPHATE IONnon-polymer95.01Chemie (PO4)
3A2-[1-[[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3-oxidanylidene-9-oxa-2,5-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-5-yl]carbonyl]piperidin-4-yl]ethanoic acidnon-polymer600.11Chemie (KUO)
4waterwater18.0324Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39166.7
Non-Polymers*Number of molecules2
Total formula weight695.1
All*Total formula weight39861.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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