8WTF
The Crystal Structure of IRAK4 from Biortus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-1 receptor-associated kinase 4 | polymer | 297 | 33312.9 | 1 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4,Renal carcinoma antigen NY-REN-64 |
| 2 | B (A) | 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | non-polymer | 361.4 | 1 | Chemie (8CG) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | G (A) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A: 164 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Asn 311 | Asp 311 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33312.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 643.6 | |
| All* | Total formula weight | 33956.5 |
