8WSQ
A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Fusion glycoprotein F0 | polymer | 474 | 52296.8 | 1 | UniProt (C3UPB8) Pfam (PF00523) UniProt (by SIFTS) (P03420) In PDB | Respiratory syncytial virus | |
2 | A | RV11-H scFv | polymer | 133 | 14823.2 | 1 | Homo sapiens (human) | ||
3 | B | RV11-L scFv | polymer | 132 | 13757.2 | 1 | Homo sapiens (human) |
Sequence modifications
F: 40 - 513 (UniProt: C3UPB8)
PDB | External Database | Details |
---|---|---|
Glu 105 | Lys 66 | conflict |
Val 115 | Ile 76 | conflict |
- | Asn 104 | deletion |
- | Asn 105 | deletion |
- | Arg 106 | deletion |
- | Ala 107 | deletion |
- | Arg 108 | deletion |
- | Arg 109 | deletion |
- | Glu 110 | deletion |
- | Leu 111 | deletion |
- | Pro 112 | deletion |
- | Arg 113 | deletion |
- | Phe 114 | deletion |
- | Met 115 | deletion |
- | Asn 116 | deletion |
- | Tyr 117 | deletion |
- | Thr 118 | deletion |
- | Leu 119 | deletion |
- | Asn 120 | deletion |
- | Asn 121 | deletion |
- | Ala 122 | deletion |
- | Lys 123 | deletion |
- | Lys 124 | deletion |
- | Thr 125 | deletion |
- | Asn 126 | deletion |
- | Val 127 | deletion |
- | Thr 128 | deletion |
- | Leu 129 | deletion |
- | Ser 130 | deletion |
- | Lys 131 | deletion |
- | Lys 132 | deletion |
- | Arg 133 | deletion |
- | Lys 134 | deletion |
- | Arg 135 | deletion |
- | Arg 136 | deletion |
- | Phe 137 | deletion |
- | Leu 138 | deletion |
- | Gly 139 | deletion |
- | Phe 140 | deletion |
- | Leu 141 | deletion |
- | Leu 142 | deletion |
Ser 144 | Val 144 | conflict |
Cys 155 | Ser 155 | conflict |
Phe 190 | Ser 190 | conflict |
Leu 207 | Val 207 | conflict |
Cys 290 | Ser 290 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 80877.2 | |
All* | Total formula weight | 80877.2 |