8WSQ
A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Fusion glycoprotein F0 | polymer | 474 | 52296.8 | 1 | UniProt (C3UPB8) Pfam (PF00523) UniProt (by SIFTS) (P03420) | Respiratory syncytial virus | |
| 2 | B (A) | RV11-H scFv | polymer | 133 | 14823.2 | 1 | Homo sapiens (human) | ||
| 3 | C (B) | RV11-L scFv | polymer | 132 | 13757.2 | 1 | Homo sapiens (human) |
Sequence modifications
F: 40 - 513 (UniProt: C3UPB8)
| PDB | External Database | Details |
|---|---|---|
| Glu 105 | Lys 66 | conflict |
| Val 115 | Ile 76 | conflict |
| - | Asn 104 | deletion |
| - | Asn 105 | deletion |
| - | Arg 106 | deletion |
| - | Ala 107 | deletion |
| - | Arg 108 | deletion |
| - | Arg 109 | deletion |
| - | Glu 110 | deletion |
| - | Leu 111 | deletion |
| - | Pro 112 | deletion |
| - | Arg 113 | deletion |
| - | Phe 114 | deletion |
| - | Met 115 | deletion |
| - | Asn 116 | deletion |
| - | Tyr 117 | deletion |
| - | Thr 118 | deletion |
| - | Leu 119 | deletion |
| - | Asn 120 | deletion |
| - | Asn 121 | deletion |
| - | Ala 122 | deletion |
| - | Lys 123 | deletion |
| - | Lys 124 | deletion |
| - | Thr 125 | deletion |
| - | Asn 126 | deletion |
| - | Val 127 | deletion |
| - | Thr 128 | deletion |
| - | Leu 129 | deletion |
| - | Ser 130 | deletion |
| - | Lys 131 | deletion |
| - | Lys 132 | deletion |
| - | Arg 133 | deletion |
| - | Lys 134 | deletion |
| - | Arg 135 | deletion |
| - | Arg 136 | deletion |
| - | Phe 137 | deletion |
| - | Leu 138 | deletion |
| - | Gly 139 | deletion |
| - | Phe 140 | deletion |
| - | Leu 141 | deletion |
| - | Leu 142 | deletion |
| Ser 144 | Val 144 | conflict |
| Cys 155 | Ser 155 | conflict |
| Phe 190 | Ser 190 | conflict |
| Leu 207 | Val 207 | conflict |
| Cys 290 | Ser 290 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 80877.2 | |
| All* | Total formula weight | 80877.2 |
