8WSM
NLRP3 NACHT domain in complex with compound 32
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 550 | 64156.3 | 1 | UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) | Homo sapiens (human) | |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 4 | D (A) | 2-[[2-methyl-5-(trifluoromethyl)phenyl]amino]-~{N}-(1,4-oxazepan-4-ylsulfonyl)-1,3-oxazole-4-carboxamide | non-polymer | 448.4 | 1 | Chemie (XE3) | |||
| 5 | E (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 131 - 679 (UniProt: Q96P20)
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 64156.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 899.9 | |
| All* | Total formula weight | 65056.2 |
