8WSJ
Crystal structure of SARS-Cov-2 main protease, pH=6.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C-like proteinase nsp5 | polymer | 295 | 32683.3 | 1 | UniProt (P0DTC1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | B (B) | 3C-like proteinase nsp5 | polymer | 299 | 33148.8 | 1 | UniProt (P0DTC1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 3 | C, D (A, B) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
B: 3 - 301 (UniProt: P0DTC1)
| PDB | External Database | Details |
|---|---|---|
| Leu 140 | Phe 3403 | conflict |
| Phe 141 | Leu 3404 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65832.1 | |
| All* | Total formula weight | 65832.1 |
