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8WO3

Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Mupirocin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoleucine--tRNA ligasepolymer921106320.61UniProt (A0A2J9KLI1)
Pfam (PF00133)
Pfam (PF08264)
UniProt (by SIFTS) (P56456)
Helicobacter pylori (Campylobacter pylori)Isoleucyl-tRNA synthetase,IleRS
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D, E
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
4F
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5G
(A)
MUPIROCINnon-polymer500.61Chemie (MRC)
6H
(A)
waterwater18.0455Chemie (HOH)
Sequence modifications
A: 1 - 920 (UniProt: A0A2J9KLI1)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight106320.6
Non-Polymers*Number of molecules6
Total formula weight901.4
All*Total formula weight107222.0
*Water molecules are not included.

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PDB entries from 2025-07-16

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