8WO3

Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Mupirocin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA editing activity
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004822	molecular_function	isoleucine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006428	biological_process	isoleucyl-tRNA aminoacylation
A	0008270	molecular_function	zinc ion binding
A	0046872	molecular_function	metal ion binding
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	12
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PyaNGhLHLGHA

Chain	Residue	Details
A	PRO58-ALA69

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02002

Chain	Residue	Details
A	GLU569
A	LYS613
A	CYS895
A	CYS898
A	CYS910
A	CYS913

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