8WMP
Crystal Structure of Mutant HisB from Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Imidazoleglycerol-phosphate dehydratase | polymer | 217 | 23732.6 | 1 | UniProt (A0A0T7LD88) Pfam (PF00475) UniProt (by SIFTS) (P9WML9) | Mycobacterium tuberculosis | |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | G (A) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A: 1 - 210 (UniProt: A0A0T7LD88)
| PDB | External Database | Details |
|---|---|---|
| Met -6 | - | initiating methionine |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Gln 5 | Glu 5 | engineered mutation |
| Ala 124 | Cys 124 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23732.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 313.5 | |
| All* | Total formula weight | 24046.2 |
