8WHI

Crystal structure of native CLASP2 in complex with CLIP170

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CLIP-associating protein 2	polymer	235	26443.8	1	UniProt (O75122) In PDB	Homo sapiens (human)	Cytoplasmic linker-associated protein 2,Protein Orbit homolog 2,hOrbit2
2	E, F	CLIP1 protein	polymer	111	12689.1	2	UniProt (Q6P5Z9) In PDB	Homo sapiens (human)
3	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5		water	water		18.0	260	Chemie (HOH)

Sequence modifications

A: 1251 - 1479 (UniProt: O75122)

PDB	External Database	Details
Gly 1245	-	expression tag
Pro 1246	-	expression tag
Gly 1247	-	expression tag
Ser 1248	-	expression tag
Glu 1249	-	expression tag
Phe 1250	-	expression tag

E, F: 350 - 456 (UniProt: Q6P5Z9)

PDB	External Database	Details
Gly 346	-	expression tag
Pro 347	-	expression tag
Gly 348	-	expression tag
Ser 349	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	51821.9
Non-Polymers*	Number of molecules	4
	Total formula weight	292.3
All*	Total formula weight	52114.3

*Water molecules are not included.