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8WFP

Crystal structure of polo-like kinase(PLK1)PBD in complex with DD-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine/threonine-protein kinase PLK1polymer22626052.72UniProt (P53350)
Pfam (PF00659)
Homo sapiens (human)Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13
2C, D
(C, D)
DD-1polymer7658.62Homo sapiens
3E, F, G, H
(A, B, C, D)
waterwater18.0232Chemie (HOH)
Sequence modifications
A, B: 373 - 596 (UniProt: P53350)
PDBExternal DatabaseDetails
Ala 371-expression tag
Ala 372-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight53422.8
All*Total formula weight53422.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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