8WDE
CryoEM structure of the spike protein of human CoV 229E in complex with receptor hAPN (composite map)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1165 | 127915.5 | 3 | Pfam (PF01600) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (P15423) | Human coronavirus 229E | |
| 2 | D, E (D, E) | Aminopeptidase N | polymer | 943 | 107906.7 | 2 | UniProt (P15144) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) | Homo sapiens (human) | |
| 3 | F, H, J (F, H, J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 4 | G, I, K, L (G, I, K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, BA, CA, DA, EA... (C, D, E, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 20 | Chemie (NAG) |
Sequence modifications
D, E: 66 - 967 (UniProt: P15144)
| PDB | External Database | Details |
|---|---|---|
| Gln 968 | - | expression tag |
| Asp 969 | - | expression tag |
| Asn 970 | - | expression tag |
| Ser 971 | - | expression tag |
| Ala 972 | - | expression tag |
| Asp 973 | - | expression tag |
| Ile 974 | - | expression tag |
| Gln 975 | - | expression tag |
| His 976 | - | expression tag |
| Ser 977 | - | expression tag |
| Gly 978 | - | expression tag |
| Arg 979 | - | expression tag |
| Pro 980 | - | expression tag |
| Leu 981 | - | expression tag |
| Glu 982 | - | expression tag |
| Ser 983 | - | expression tag |
| Arg 984 | - | expression tag |
| Gly 985 | - | expression tag |
| Pro 986 | - | expression tag |
| Phe 987 | - | expression tag |
| Glu 988 | - | expression tag |
| Gln 989 | - | expression tag |
| Lys 990 | - | expression tag |
| Leu 991 | - | expression tag |
| Ile 992 | - | expression tag |
| Ser 993 | - | expression tag |
| Glu 994 | - | expression tag |
| Glu 995 | - | expression tag |
| Asp 996 | - | expression tag |
| Leu 997 | - | expression tag |
| Asn 998 | - | expression tag |
| Met 999 | - | expression tag |
| His 1000 | - | expression tag |
| Thr 1001 | - | expression tag |
| Gly 1002 | - | expression tag |
| His 1003 | - | expression tag |
| His 1004 | - | expression tag |
| His 1005 | - | expression tag |
| His 1006 | - | expression tag |
| His 1007 | - | expression tag |
| His 1008 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 599559.9 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 3457.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 4424.2 | |
| All* | Total formula weight | 607441.3 |
