8W7H
Purine Nucleoside Phosphorylase in complex with MMV000848
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Purine nucleoside phosphorylase | polymer | 252 | 27791.1 | 1 | UniProt (Q8I3X4) Pfam (PF01048) In PDB | Plasmodium falciparum 3D7 | |
| 2 | A | (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol | non-polymer | 308.4 | 1 | Chemie (XUH) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 1 - 245 (UniProt: Q8I3X4)
| PDB | External Database | Details |
|---|---|---|
| Ala 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27791.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 511.4 | |
| All* | Total formula weight | 28302.6 |
