8W4M
Crystal structure of open conformation of human immunoglobulin Fc in presence of EndoSz
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Immunoglobulin gamma-1 heavy chain | polymer | 223 | 25129.5 | 1 | UniProt (P0DOX5) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 1 | In PDB GlyTouCan (G27919IH) | |||
| 3 | C, D, E, F, G... (A) | ZINC ION | non-polymer | 65.4 | 10 | Chemie (ZN) | |||
| 4 | M (A) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence modifications
A: 225 - 447 (UniProt: P0DOX5)
| PDB | External Database | Details |
|---|---|---|
| Glu 356 | Asp 358 | variant |
| Met 358 | Leu 360 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25129.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1625.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 654.1 | |
| All* | Total formula weight | 27409.1 |
