8W34

HIV-1 intasome core assembled with wild-type integrase, 1F

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, G... (A, B, C, D, I...)	Integrase	polymer	288	32244.8	8	UniProt (F2WR39) UniProt (by SIFTS) (P12497)	Human immunodeficiency virus 1
2	E, K (E, N)	DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*AP*C)-3')	polymer	90	27371.4	2		synthetic construct
3	F, L (F, O)	DNA (5'-D(P*GP*TP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3')	polymer	27	8374.5	2		synthetic construct
4	M, Q (A, I)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	N, R (A, I)	(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide	non-polymer		419.4	2	Chemie (DLU)
6	O, P, S, T (A, I)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	329450.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1066.8
All*	Total formula weight	330516.9

*Water molecules are not included.