8W2F
Plasmodium falciparum 20S proteasome bound to an inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, N (A, O) | Proteasome endopeptidase complex | polymer | 260 | 29531.7 | 2 | UniProt (Q8IAR3) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 2 | B, O (B, P) | Proteasome endopeptidase complex | polymer | 235 | 26556.4 | 2 | UniProt (C6KST3) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 3 | C, P (C, Q) | Proteasome subunit alpha type | polymer | 242 | 27443.0 | 2 | UniProt (Q8IDG3) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 4 | D, Q (D, R) | Proteasome subunit alpha type | polymer | 241 | 27263.3 | 2 | UniProt (Q8IDG2) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 5 | E, R (E, S) | Proteasome subunit alpha type | polymer | 256 | 28417.4 | 2 | UniProt (Q8IBI3) Pfam (PF00227) Pfam (PF10584) | Plasmodium falciparum 3D7 | |
| 6 | F, S (F, T) | Proteasome endopeptidase complex | polymer | 254 | 28871.7 | 2 | UniProt (Q8IK90) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 7 | G, T (G, U) | Proteasome subunit alpha type-3, putative | polymer | 252 | 29324.3 | 2 | UniProt (O77396) Pfam (PF10584) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 8 | H, U (H, V) | Proteasome subunit beta type-6, putative | polymer | 252 | 29143.9 | 2 | UniProt (Q8I0U7) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 9 | AA, I (I, W) | Proteasome subunit beta | polymer | 229 | 25104.9 | 2 | UniProt (Q8I6T3) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 10 | J, V (J, X) | Proteasome subunit beta | polymer | 218 | 24533.1 | 2 | UniProt (Q8I261) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 11 | K, W (K, Y) | Proteasome subunit beta | polymer | 195 | 22889.1 | 2 | UniProt (Q8IKC9) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 12 | L, X (L, Z) | Proteasome subunit beta type | polymer | 211 | 23620.6 | 2 | UniProt (Q8IJT1) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 13 | BA, M (N, b) | Proteasome subunit beta | polymer | 284 | 33155.2 | 2 | UniProt (Q7K6A9) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 14 | Y, Z (M, a) | Proteasome subunit beta | polymer | 240 | 27301.2 | 2 | UniProt (A0A5K1K7U1) Pfam (PF00227) | Plasmodium falciparum 3D7 | |
| 15 | CA, DA (M, a) | (3S)-1-[(2-fluoroethoxy)acetyl]-N-{[(4P)-4-(6-methylpyridin-3-yl)-1,3-thiazol-2-yl]methyl}piperidine-3-carboxamide | non-polymer | 420.5 | 2 | Chemie (A1AE6) |
Sequence modifications
N, b: 1 - 265 (UniProt: Q7K6A9)
| PDB | External Database | Details |
|---|---|---|
| Gly 266 | - | expression tag |
| Ser 267 | - | expression tag |
| Gly 268 | - | expression tag |
| Ser 269 | - | expression tag |
| Glu 270 | - | expression tag |
| Asn 271 | - | expression tag |
| Leu 272 | - | expression tag |
| Tyr 273 | - | expression tag |
| Phe 274 | - | expression tag |
| Gln 275 | - | expression tag |
| Gly 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
| His 280 | - | expression tag |
| His 281 | - | expression tag |
| His 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 766311.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 841.0 | |
| All* | Total formula weight | 767152.7 |
